Blog Archives

NIH Requests Information on ECHO-wide Cohort Data Collection Protocol

The National Institutes of Health (NIH) is seeking input into the development of the cohort data collection protocol for the Environmental influences on Child Health Outcomes (ECHO) program. ECHO was formed late last year to “investigate how exposure to a range of environmental factors in early development—from conception through early childhood–influences the health of children and adolescents.” ECHO represents the follow-on activity to the now-discontinued National Children’s Study.

The Request for Information seeks comments on a number of aspects of the ECHO-wide cohort, which will entail data collection from 84 existing cohorts. Input is sought on the data elements, types of biospecimens, and innovative data collection methodology associated with the cohort.

The deadline for comments has been extended to September 13.

Back to this issue’s table of contents.

Tagged with: , ,
Posted in Issue 17 (September 5), Update, Volume 36 (2017)

NIH Launches ECHO Program

On September 21, the National Institutes of Health (NIH) announced the launch of the seven-year Environmental Influences on Children Health Outcomes (ECHO) program designed to “investigate how exposure to a range of environmental factors in early development–from conception through early childhood–influences the health of children and adolescents.” The agency planned to allocate $157 million in funding in fiscal year (FY) 2016 for ECHO. Presenting at the September 21 National Advisory Child Health and Human Development (NACHHD) Council, ECHO Director Matthew Gillman outlined the goals of the study. Gillman noted that the aims for ECHO are consistent with the agency’s goals for the now discontinued National Children’s Study, however, the approach is different.
In addition to examining such exposures as air pollution, ECHO will also examine “societal factors such as stress, to individual behaviors like sleep and diet.” The program will use the Institutional Development Awards (IDeA) program to create pediatric clinical research networks in rural and medically underserved areas in an effort to allow children in these areas the opportunity to participate in clinical trials. The ECHO infrastructure will include: pediatric cohorts, a coordinating center, a data analysis center, the Children’s Health and Exposure Analysis Resource (CHEAR) core, a Patient Reported Outcomes (PRO) core, and an IDeA States Pediatric Clinical Trials Network (ISPCTN), which has been funded up front for four years.
Tagged with: , , , ,
Posted in Issue 19 (October 4), Update, Volume 35 (2016)

NIH Director Fills Vacancies for PMI Cohort and ECHO Programs

National Institute of Health (NIH) Director Francis Collins recently announced the appointments of Eric Dishman as the Director of the Precision Medicine Initiative (PMI) Cohort Program and Matthew Gillman as the Program Director of the NIH Environmental Influences on Child Health Outcomes (ECHO). (more…)

Tagged with: , , ,
Posted in Issue 9 (May 3), Update, Volume 35 (2016)

NIH Launches Next Phase of ECHO/Children’s Study Follow-On

On December 7, National Institutes of Health (NIH) director Francis Collins announced the next funding phase of the agency’s Environmental Influences on Child Health Outcomes (ECHO) program, which includes seven new funding opportunity announcements (FOAs). ECHO is designed to comport with the goals of the National Children’s Study (NCS) (see Update, November 3, 2015) and is being implemented via a series of funding opportunity announcements (FOAs). It is expected that the ECHO program will be supported by and build on recent awards NIH made in September (see Update, September 4, 2015). A nationwide search is underway for an ECHO program manager. In the interim, NIH Deputy Director Lawrence Tabak will continue to lead the program.

ECHO program funding opportunities:

  1. Clinical Sites for the IDeA States Pediatric Clinical Trials Network (UG1) RFA-OD-16-001
  2. Data Coordinating and Operations Center for the IDeA States Pediatric Clinical Trials Network (U24) RFA-OD-16-002
  3. Environmental Influences on Child Health Outcomes: Patient Reported Outcomes Research Resource Center Core (ECHO PRO Core) (U24) RFA-OD-16-003
  4. Environmental influences on Child Health Outcomes (ECHO) Pediatric Cohorts (UG3/UH3) RFA-OD-16-004
  5. Environmental Influences on Child Health Outcomes (ECHO) Data Analysis Center (U24) RFA-OD-16-005
  6. Environmental Influences on Child Health Outcomes (ECHO) Coordinating Center (U2C) RFA-OD-16-006
  7. Limited Competition: Exposure Analysis Services for the Environmental Influences on Children’s Health Outcomes (ECHO) Program (Admin Supplement) PA-16-046

Back to this issue’s table of contents.

Tagged with: , , , ,
Posted in Issue 23 (December 15), Update, Volume 34 (2015)

NIH Announces Plans for ECHO Program

The National Institutes of Health (NIH) recently issued a notice, Announcement of NIH Plans for the Environmental Influences on Child Health Outcomes (ECHO) Program (NOT-OD-16-015), detailing the agency’s plans for program, also known as the National Children’s Study (NCS) alternative (see Update, July 17, 2015). The agency reports that it intends to “support multiple synergistic, longitudinal studies using extant maternal/pediatric cohorts that represent a broad range of environmental exposures,” including behavioral and social exposures. According to the notice, “all longitudinal studies will collect a standardized, targeted set of data (Core Elements), such as demographics, normative development, patient/person reported outcomes (PRO), environmental exposures, and genetic influences.” ECHO-supported studies will focus on four key pediatric outcomes or focus areas: (1) upper and lower airway; (2) obesity; (3) pre-, peri-, and postnatal outcomes; and (4) neurodevelopment. The program will also seek to “leverage the existing Institutional Development Award (IDeA) infrastructure” through its inclusion of a States Pediatric Clinical Trials Network.

Back to this issue’s table of contents.

Tagged with: , , ,
Posted in Issue 20 (November 3), Update, Volume 34 (2015)

Subscribe

Click here to subscribe to the COSSA Washington Update, our biweekly newsletter.

Archive

Looking for something from a previous issue of the COSSA Washington Update? Try our archive.

Issues

Browse by Month