The National Institutes of Health’s (NIH) All of Us Research Program (formerly the Precision Medicine Initiative Cohort Program) within NIH Office of the Director has issued a new funding opportunity for organizations interested in helping engage volunteers. The funding opportunity is open to national and regional organizations, as well as local community groups. The program is designed to support activities to promote enrollment and retention in the All of Us Research Program across diverse communities. All of Us, unlike the majority of NIH-supported research, is not focused on a particular disease or population. The program is intended to “serve as a national research resource to inform thousands of studies, covering a wide variety of health conditions.” The agency plans to launch the All of Us program later this year.